National Institute on Drug Abuse (NIDA)
The Brain: Understanding Neurobiology Through the Study of Addiction
This is a curriculum supplement for grades 9 - 12. It covers the fundamentals of neurobiology, and shows how drugs of abuse change the brain. This resource is from the US National Institute of Health (NIH).
Neurobiology of addictive behaviors and its relationship to methadone maintenance
About the studies and research of the neurobiology of addictive behaviours to support opioid agonist pharmacotherapy, primarily methadone maintenance treatment, for long-term heroin addiction. This paper is by Barry Stimmel and Mary Jeanne Kreek. 2000
Neuoroscience of Addiction
By George F Koob and Amanda Roberts. Neuron, Vol. 21, 467-476, September, 1998. This article considers the impact of addiction on neurobiological processes.
Neuroadaptative changes in dopaminergic and glutamatergic systems during cocaine withdrawal
By Emilio Ambrosio and J.A. Crespo. A paper given at the 6th Internet World Congress for Biomedical Sciences in 2000 on recent advances in the neurobiology of drug addiction. In this work the authors present evidence on neuroadaptations of dopaminergic and glutamatergic systems during cocaine withdrawal. 2000
Genome Map Adds Valuable Information to Mystery of Drug Addiction
A report on the human genome-mapping project which is leading to a better understanding of how drugs act on brain pathways to cause addiction. 2001
The Wheeler Center for the Neurobiology of Addiction
This is the website for The Wheeler Center for the Neurobiology of Addiction. The Center is based at University of California, San Francisco. It brings together core faculty in cellular, molecular and systems neurosciences to explore and identify the neural circuits, molecular targets and biochemical actions that help drugs of abuse take command of the brain. This site contains information about the Center, plus information on activities, news, reports, etc. It also contains a forum for further discussion on this issue.
World Health Organization (WHO)
Neuroscience of Psychoactive Substance Use and Dependence
An authoritative summary of current knowledge of the biological basis of substance use behaviours. The report focuses on a wide range of psychoactive substances, including tobacco, alcohol and illicit drugs. New developments in neuroscience research are discussed (e.g., mechanisms governing craving, tolerance, neuroadaptation, immunotherapies and the concept of dependence) as well the ethical implications of these developments. It is expected that this publication will be of interest to health care workers, clinicians, social workers, university students, science teachers and informed policy makers. 2004
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